Article
The frequency of CYP2C9, VKORC1, and CYP4F2 polymorphisms in Russian patients with high thrombotic risk.
Medicina (Kaunas, Lithuania) - 1 Jan 2013
Ivashchenko Dmitriy, Rusin Ilya, Sychev Dmitriy, Grachev Andrey
Abstract excerpt
BACKGROUND AND OBJECTIVE: VKORC1, CYP2C9, and CYP4F2 are known to be responsible for the metabolism of warfarin. The aim was to explore the frequencies of these genotypes in the Russian population and compare the results with those for other populations. MATERIAL AND METHODS: In total, 91 Caucasian subjects with a mean age of 66.17 years (SD, 10.9) were recruited into the study. Of them, 40 patients (48.2%) were...
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