Article
FREQUENCY OF VKORC1 AND CYP2C9 GENES POLYMORPHISM IN ABKHAZIAN POPULATION.
Georgian medical news - 1 May 2023
Lezhava T, Kakauridze N, Jokhadze T, Buadze T, Gaiozishvili M, Gargulia Kh, Sigua T
Abstract excerpt
The aim of the research was to study the frequency of VKROC1 and CYP2C9 genes different alleles for healthy donors and for patients with thrombosis, in Abkhazian population and to reveal the interdependence of the studied genes products in the treatment of thrombosis with warfarin. Warfarin is an anticoagulant, causing the inactivation of the VKORC1 gene product, which is one of the clotting factors. The protein...
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