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Article

Frequency of selected single nucleotide polymorphisms influencing the warfarin pharmacogenetics in Slovak population.

European journal of haematology - 1 Oct 2014

Krajčíová L'ubica, Petrovič Robert, Déžiová L'udmila, Chandoga Ján, Turčáni Peter

Abstract excerpt

OBJECTIVE: Warfarin represents the most commonly prescribed oral anticoagulants, which functions as an antagonist of vitamin K, an essential factor of blood coagulation cascade. Warfarin has a narrow therapeutic index. An insufficient dose can cause failure of antithrombotic effect, and an overdose increases a risk of bleeding. It is known that variability in two genes (CYP2C9 and VKORC1) has a significant effect...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24750390
DOI: 10.1111/ejh.12348

Genes

VKORC1
GGCX

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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