Article
Endothelin-1 gene polymorphisms influence cerebrospinal fluid endothelin-1 levels following aneurysmal subarachnoid hemorrhage.
Biological research for nursing - 1 Mar 2015
Gallek Matthew J, Alexander Sheila A, Crago Elizabeth, Sherwood Paula R, Klamerus Megan, Horowitz Michael B, Poloyac Samuel M, Conley Yvette
Abstract excerpt
Aneurysmal subarachnoid hemorrhage is a type of stroke with high morbidity and mortality. Increased endothelin-1 (ET-1) levels have been associated with increased risk of cerebral vasospasm, which is associated with increased morbidity. The purpose of this study was to investigate the relationships between ET-1 genotypes and ET-1 protein levels in cerebrospinal fluid (CSF) measured 72 hr before angiographic...
Topics
- Endothelin-1
- Female
- Genotyping Techniques
- Humans
- Intracranial Aneurysm
- Male
- Middle Aged
- Polymorphism, Single Nucleotide
- Radiography
- Subarachnoid Hemorrhage