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Article

Endothelial nitric oxide synthase gene single-nucleotide polymorphism predicts cerebral vasospasm after aneurysmal subarachnoid hemorrhage.

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism - 1 Jun 2008

Starke Robert M, Kim Grace H, Komotar Ricardo J, Hickman Zachary L, Black Eric M, Rosales Maritza B, Kellner Christopher P, Hahn David K, Otten Marc L, Edwards John, Wang Tao, Russo James J, Mayer Stephan A, Connolly Edward S

Abstract excerpt

Vasospasm is a major cause of morbidity and mortality after aneurysmal subarachnoid hemorrhage (aSAH). Studies have shown a link between single-nucleotide polymorphisms (SNPs) in the endothelial nitric oxide synthase (eNOS) gene and the incidence of coronary spasm and aneurysms. Alterations in the eNOS T-786 SNP may lead to an increased risk of post-aSAH cerebral vasospasm. In this prospective clinical study, 77...

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Identifiers

PMID: 18319732
DOI: 10.1038/jcbfm.2008.11
PMCID: PMC2744963

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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