Article
Association of Plasminogen Activator Inhibitor 1 (SERPINE1) Polymorphisms and Aneurysmal Subarachnoid Hemorrhage.
World neurosurgery - 1 Sept 2017
Hendrix Philipp, Foreman Paul M, Harrigan Mark R, Fisher Winfield S, Vyas Nilesh A, Lipsky Robert H, Lin Minkuan, Walters Beverly C, Tubbs R Shane, Shoja Mohammadali M, Pittet Jean-Francois, Mathru Mali, Griessenauer Christoph J
Abstract excerpt
BACKGROUND: Genetic variations of the serine proteinase inhibitor family E member 1 (SERPINE1) gene, which encodes plasminogen activator inhibitor 1, correlate with serum levels of its product and are associated with thrombophilia and coronary atherosclerosis. Various SERPINE1 ;gene polymorphisms have been identified. However, only the functional 5G/4G polymorphism has been assessed in the context of aneurysmal...
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