Article
Endothelin polymorphisms as a risk factor for cerebral aneurysm rebleeding following aneurysmal subarachnoid hemorrhage.
Clinical neurology and neurosurgery - 1 Jun 2017
Foreman Paul M, Starke Robert M, Hendrix Philipp, Harrigan Mark R, Fisher Winfield S, Vyas Nilesh A, Lipsky Robert H, Lin Minkuan, Walters Beverly C, Pittet Jean-Francois, Mathru Mali, Griessenauer Christoph J
Abstract excerpt
BACKGROUND: Aneurysm rebleeding following presentation with aneurysmal subarachnoid hemorrhage (aSAH) is associated with high mortality and poor functional outcome. While a substantial genetic contribution to aneurysm formation and rupture is known, the genetic influence on the risk of rebleeding is poorly understood. OBJECTIVE: To evaluate the role of common endothelin polymorphisms in aneurysm rebleeding....
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