Article
20-HETE is associated with unfavorable outcomes in subarachnoid hemorrhage patients.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism - 1 Sept 2015
Donnelly Mark K, Crago Elizabeth A, Conley Yvette P, Balzer Jeffery R, Ren Dianxu, Ducruet Andrew F, Kochanek Patrick M, Sherwood Paula R, Poloyac Samuel M
Abstract excerpt
Emerging evidence has suggested that patients experiencing aneurysmal subarachnoid hemorrhage (aSAH) develop vascular dysregulation as a potential contributor to poor outcomes. Preclinical studies have implicated the novel microvascular constrictor, 20-hydroxyeicosatetraenoic acid (20-HETE) in aSAH pathogenesis, yet the translational relevance of 20-HETE in patients with aSAH is largely unknown. The goal of this...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.