Article
Endothelin-1 and endothelin receptor gene variants and their association with negative outcomes following aneurysmal subarachnoid hemorrhage.
Biological research for nursing - 1 Oct 2013
Gallek Matthew, Alexander Sheila, Crago Elizabeth, Sherwood Paula, Horowitz Michael, Poloyac Samuel, Conley Yvette
Abstract excerpt
Aneurysmal subarachnoid hemorrhage (aSAH) is a devastating disease that affects approximately 30,000 people a year in the United States. Delayed cerebral ischemia (DCI) and cerebral vasospasm (CV) are common complications after aSAH. In addition, aSAH patients have a high risk of poor long-term outcomes. Endothelin-1 (ET-1), a potent vasoconstrictor, or its two types of receptors, ET receptor A (ETA) and ET...
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