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Article

Endothelial nitric oxide synthase gene polymorphisms predict susceptibility to aneurysmal subarachnoid hemorrhage and cerebral vasospasm.

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism - 1 Mar 2004

Khurana Vini G, Sohni Youvraj R, Mangrum Wells I, McClelland Robyn L, O'Kane Dennis J, Meyer Fredric B, Meissner Irene

Abstract excerpt

Rupture of an intracranial aneurysm (subarachnoid hemorrhage) is a potentially devastating condition frequently complicated by delayed cerebral ischemia from sustained contraction of intracranial arteries (cerebral vasospasm). There is mounting evidence linking the formation of intracranial aneurysms and the pathogenesis of post-subarachnoid hemorrhage vasospasm to aberrant bioavailability and action of the...

Topics

Adult
Aged
Female
Genetic Predisposition to Disease
Humans
Isoenzymes
Middle Aged
Nitric Oxide Synthase
Nitric Oxide Synthase Type III
Oligonucleotide Array Sequence Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Genetic

Promoter Regions, Genetic

Prospective Studies

Subarachnoid Hemorrhage

Vasospasm, Intracranial

Source

Identifiers

PMID: 15091109
DOI: 10.1097/01.WCB.0000110540.96047.C7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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Endothelial nitric oxide synthase gene polymorphisms predict susceptibility to aneurysmal subarachnoid hemorrhage and cerebral vasospasm.PMID 15091109Read ↗

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