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DNA vaccine cocktail expressing genotype A and C HBV surface and consensus core antigens generates robust cytotoxic and antibody responses in mice and Rhesus macaques.

Cancer gene therapy - 1 Dec 2013

Obeng-Adjei N, Hutnick N A, Yan J, Chu J S, Myles D J F, Morrow M P, Sardesai N Y, Weiner D B

Abstract excerpt

There are well over a quarter of a billion chronic hepatitis B virus (HBV) carriers across the globe. Most carriers are at high risk for development of liver cirrhosis and subsequent progression to hepatocellular carcinoma. It is therefore imperative to develop new approaches for immunotherapy against this infection. Antibodies and cytotoxic T cells to different HBV antigens are believed to be important for...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24310062
DOI: 10.1038/cgt.2013.65

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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