Article
Association between latent proviral characteristics and immune activation in antiretrovirus-treated human immunodeficiency virus type 1-infected adults.
Journal of virology - 1 Aug 2014
Liang Emily C, Sceats Lindsay, Bayless Nicholas L, Strauss-Albee Dara M, Kubo Jessica, Grant Philip M, Furman David, Desai Manisha, Katzenstein David A, Davis Mark M, Zolopa Andrew R, Blish Catherine A
Abstract excerpt
UNLABELLED: Generalized immune activation during HIV infection is associated with an increased risk of cardiovascular disease, neurocognitive disease, osteoporosis, metabolic disorders, and physical frailty. The mechanisms driving this immune activation are poorly understood, particularly for individuals effectively treated with antiretroviral medications. We hypothesized that viral characteristics such as...
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