Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Topics Community

Article

Navigating the complexity of chronic HIV-1 associated immune dysregulation

11 May 2022

Abstract excerpt

Despite successful viral suppression with antiretroviral therapy, chronic HIV-1 infection is associated with ongoing immune dysfunction. Investigation of the complex immune response in treated and untreated individuals with chronic HIV-1 infection is warranted. Immune alterations such as monocyte phenotype and Th-17/Treg ratios often persist years after the reduction in viraemia and predispose many individuals to...

Topics

Join the communities discussing this publication.

HIV/AIDS drug development and treatment
HIV-related health complications and treatments
HIV Research and Treatment

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 35567953
DOI: 10.1016/j.coi.2022.102186

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Navigating the complexity of chronic HIV-1 associated immune dysregulationPMID 35567953Read ↗

Immune activation in the course of HIV-1 infection: Causes, phenotypes and persistence under therapy.Semantic proximity Read ↗

Identification of distinct HIV reservoir phenotypes and associated immune landscapes.Semantic proximity Read ↗

Insights Into Persistent HIV-1 Infection and Functional Cure: Novel Capabilities and StrategiesSemantic proximity Read ↗

HIV-infected long-term nonprogressors: epidemiology, mechanisms of delayed progression, and clinical and research implicationsSemantic proximity Read ↗

Multi-Omics Single-Cell Analysis Reveals Key Regulators of HIV-1 Persistence and Aberrant Host Immune Responses in Early InfectionSemantic proximity Read ↗

The role of naïve T-cells in HIV-1 pathogenesis: An emerging key playerSemantic proximity Read ↗

Transcriptomic crosstalk between viral and host factors drives aberrant homeostasis of T-cell proliferation and cell death in HIV-infected immunological non-respondersSemantic proximity Read ↗

Global transcriptomic characterization of T cells in individuals with chronic HIV-1 infectionSemantic proximity Read ↗

Host genetic and immune factors drive evasion of HIV-1 pathogenesis in viremic non-progressors.Semantic proximity Read ↗

AIDS pathogenesis: a dynamic interaction between HIV and the immune system.Semantic proximity Read ↗

Longitudinal transcriptomic analysis of SIV-infected rhesus macaques reveals peripheral immune dynamics throughout untreated SIV infection and long-term antiretroviral therapySemantic proximity Read ↗

Role of myeloid cells in HIV-1-host interplaySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.