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Acute HIV-1 Infection: Paradigm and Singularity

3 Mar 2025

Abstract excerpt

Acute HIV-1 infection (AHI) is a transient period where the virus causes evident damage to the immune system, including an extensive apoptosis of CD4+ T cells associated with a high level of activation and a major cytokine storm to fight the invading virus. HIV infection establishes persistence by integrating the viral genome into host cell DNA in both replicating and non-replicating forms, effectively hiding...

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PMID: 40143294
DOI: 10.3390/v17030366

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