Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Persistent T Cell Repertoire Perturbation and T Cell Activation in HIV After Long Term Treatment.

Frontiers in immunology - 1 Jan 2021

Turner Carolin T, Brown James, Shaw Emily, Uddin Imran, Tsaliki Evdokia, Roe Jennifer K, Pollara Gabriele, Sun Yuxin, Heather James M, Lipman Marc, Chain Benny, Noursadeghi Mahdad

Abstract excerpt

Objective: In people living with HIV (PLHIV), we sought to test the hypothesis that long term anti-retroviral therapy restores the normal T cell repertoire, and investigate the functional relationship of residual repertoire abnormalities to persistent immune system dysregulation. Methods: We conducted a case-control study in PLHIV and HIV-negative volunteers, of circulating T cell receptor repertoires and whole...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anti-HIV Agents
Share to Cross-Sectional Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HIV Infections

Share to HIV Long-Term Survivors

Share to Lymphocyte Activation

Share to Receptors, Antigen, T-Cell

Share to T-Lymphocytes

Share to Transcriptome

Source

Open in PubMed Open full text

Identifiers

PMID: 33732256
DOI: 10.3389/fimmu.2021.634489
PMCID: PMC7959740

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Persistent T Cell Repertoire Perturbation and T Cell Activation in HIV After Long Term Treatment.PMID 33732256Read ↗

Global transcriptomic characterization of T cells in individuals with chronic HIV-1 infectionSemantic proximity Read ↗

Multifaceted B-cell response to transient HIV viraemia in elite controllersSemantic proximity Read ↗

Supranormal thymic output up to 2 decades after HIV-1 infection.Semantic proximity Read ↗

HIV evolution and diversity in ART-treated patients.Semantic proximity Read ↗

Transcriptomic crosstalk between viral and host factors drives aberrant homeostasis of T-cell proliferation and cell death in HIV-infected immunological non-respondersSemantic proximity Read ↗

HIV proviral genetic diversity, compartmentalization and inferred dynamics in lung and blood during long-term suppressive antiretroviral therapy.Semantic proximity Read ↗

HIV-1 proviral landscapes distinguish posttreatment controllers from noncontrollersSemantic proximity Read ↗

Plasma Virome of HIV-infected Subjects on Suppressive Antiretroviral Therapy Reveals Association of Differentially Abundant Viruses with Distinct T-cell Phenotypes and InflammationSemantic proximity Read ↗

HIV-1–infected T cell clones are shared across cerebrospinal fluid and blood during ARTSemantic proximity Read ↗

The Landscape of Persistent Viral Genomes in ART-Treated SIV, SHIV, and HIV-2 InfectionsSemantic proximity Read ↗

Association between latent proviral characteristics and immune activation in antiretrovirus-treated human immunodeficiency virus type 1-infected adults.Semantic proximity Read ↗

Why the HIV Reservoir Never Runs Dry: Clonal Expansion and the Characteristics of HIV-Infected Cells Challenge Strategies to Cure and Control HIV InfectionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.