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Article

Tissue-specific deletion of Crry from mouse proximal tubular epithelial cells increases susceptibility to renal ischemia-reperfusion injury.

Kidney international - 1 Oct 2014

Miao Jing, Lesher Allison M, Miwa Takashi, Sato Sayaka, Gullipalli Damodar, Song Wen-Chao

Abstract excerpt

The murine cell surface protein Crry (complement receptor 1-related protein/gene y) is a key complement regulator with similar activities to human membrane cofactor protein (MCP) and decay-accelerating factor. MCP has a critical role in preventing complement-mediated tissue injury and its mutation has been implicated in several human kidney diseases. The study of Crry in mice has relevance to understanding MCP...

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Identifiers

PMID: 24850152
DOI: 10.1038/ki.2014.103
PMCID: PMC4182132

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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