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Article

Tubule-specific ablation of endogenous β-catenin aggravates acute kidney injury in mice.

Kidney international - 1 Sept 2012

Zhou Dong, Li Yingjian, Lin Lin, Zhou Lili, Igarashi Peter, Liu Youhua

Abstract excerpt

β-Catenin is a unique intracellular protein functioning as an integral component of the cell-cell adherens complex and a principal signaling protein mediating canonical Wnt signaling. Little is known about its function in adult kidneys in the normal physiologic state or after acute kidney injury (AKI). To study this, we generated conditional knockout mice in which the β-catenin gene was specifically disrupted in...

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Identifiers

PMID: 22622501
DOI: 10.1038/ki.2012.173
PMCID: PMC3425732

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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