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Article

Distinct roles for the complement regulators factor H and Crry in protection of the kidney from injury.

Kidney international - 1 Jul 2016

Laskowski Jennifer, Renner Brandon, Le Quintrec Moglie, Panzer Sarah, Hannan Jonathan P, Ljubanovic Danica, Ruseva Marieta M, Borza Dorin-Bogdan, Antonioli Alexandra H, Pickering Matthew C, Holers V Michael, Thurman Joshua M

Abstract excerpt

Mutations in the complement regulatory proteins are associated with several different diseases. Although these mutations cause dysregulated alternative pathway activation throughout the body, the kidneys are the most common site of injury. The susceptibility of the kidney to alternative pathway-mediated injury may be due to limited expression of complement regulatory proteins on several tissue surfaces within the...

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Identifiers

PMID: 27165610
DOI: 10.1016/j.kint.2016.02.036
PMCID: PMC4912413

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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