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Article

The complement system in systemic lupus erythematosus: an update.

Annals of the rheumatic diseases - 1 Sept 2014

Leffler Jonatan, Bengtsson Anders A, Blom Anna M

Abstract excerpt

The complement system plays a major role in the autoimmune disease, systemic lupus erythematosus (SLE). However, the role of complement in SLE is complex since it may both prevent and exacerbate the disease. In this review, we explore the latest findings in complement-focused research in SLE. C1q deficiency is the strongest genetic risk factor for SLE, although such deficiency is very rare. Various recently...

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Identifiers

PMID: 24845390
DOI: 10.1136/annrheumdis-2014-205287

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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