Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Complement deficiencies and systemic lupus erythematosus

1 Jan 2007

Abstract excerpt

The complement system involves both the innate and the adaptive immune systems and has important roles in the pathogenesis of SLE. Complement deficiencies within the classical pathway (C1q, C4 and C2) of activation predispose for development of the autoimmune disease SLE. The association between complement deficiencies and SLE could be explained by several mechanisms, including impaired clearance of immune...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Complement system in diseases
Share to Renal Diseases and Glomerulopathies
Share to Systemic Lupus Erythematosus Research

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 18075790
DOI: 10.1080/08916930701510673

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Complement deficiencies and systemic lupus erythematosusPMID 18075790Read ↗

The complement system in systemic lupus erythematosus: an update.Semantic proximity Read ↗

Systemic Lupus Erythematosus and Deficiencies of Early Components of the Complement Classical PathwaySemantic proximity Read ↗

The Role of Complement in the Development of Systemic Lupus ErythematosusSemantic proximity Read ↗

Complement deficiencies in humans and animals: Links to autoimmunitySemantic proximity Read ↗

SLE and Serum Complement: Causative, Concomitant or Coincidental?Semantic proximity Read ↗

Complement deficiency and autoimmunity.Semantic proximity Read ↗

Mechanisms of Disease: the complement system and the pathogenesis of systemic lupus erythematosusSemantic proximity Read ↗

Canonical and noncanonical functions of complement in systemic lupus erythematosusSemantic proximity Read ↗

Complement, infection, and autoimmunitySemantic proximity Read ↗

A protective role for innate immunity in systemic lupus erythematosus.Semantic proximity Read ↗

Systemic lupus erythematosus as the paradigm for understanding the complex immune relationships and therapeutic opportunities for targeting complement in autoimmune diseasesSemantic proximity Read ↗

Systemic lupus erythematosus and complement deficiency: clues to a novel role for the classical complement pathway in the maintenance of immune toleranceSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.