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Increased repetitive self-grooming occurs in Pax2 mutant mice generated using CRISPR/Cas9.

Behavioural brain research - 1 Sept 2020

Wei Hongen, Wang Min, Lv Na, Yang Hua, Zhao Min, Huang Bo, Li Rongshan

Abstract excerpt

Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by impaired social interaction and communication, and repetitive or restricted interest and behaviors. However, the specific pathogenesis of ASD is still unclear. It has been widely accepted that genetic and environmental risk factors are associated with the pathogenesis of ASD. Paired box2 (Pax2) gene encodes a transcription factor...

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PMID: 32653558
DOI: 10.1016/j.bbr.2020.112803

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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