Article
Epigenetic deregulation in myeloid malignancies.
Translational research : the journal of laboratory and clinical medicine - 1 Jan 2015
Meldi Kristen M, Figueroa Maria E
Abstract excerpt
Abnormal epigenetic patterning commonly is observed in cancer, including the myeloid malignancies acute myeloid leukemia and myelodysplastic syndromes. However, despite the universal nature of epigenetic deregulation, specific subtypes of myeloid disorders are associated with distinct epigenetic profiles, which accurately reflect the biologic heterogeneity of these disorders. In addition, mutations and genetic...
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