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Article

The evolution of epigenetic therapy in myelodysplastic syndromes and acute myeloid leukemia.

Seminars in hematology - 1 Jan 2021

Gonzalez-Lugo Jesus D, Chakraborty Samarpana, Verma Amit, Shastri Aditi

Abstract excerpt

Mutations in the group of epigenetic modifiers are the largest group of mutated genes in Myelodysplastic Syndromes (MDS) and are very frequently found in Acute Myeloid Leukemia (AML). Our advancements in the understanding of epigenetics in these diseases have helped develop groundbreaking therapeutics that have changed the treatment landscape of MDS and AML, significantly improving outcomes. In this review we...

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Source

Identifiers

PMID: 33509444
DOI: 10.1053/j.seminhematol.2020.12.003

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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