Article

Single-Cell Transcriptomes and Immune Repertoires Reveal the Cell State and Molecular Changes in Pemphigus Vulgaris

2023-04-14

Abstract excerpt

<h4>ABSTRACT</h4> The etiology and pathogenesis of pemphigus vulgaris (PV) are closely related to both immune cells and epithelial cells, but the specific subtypes of immune cells involved in PV and their roles are not yet fully understood. Additionally, the specific functions and mechanisms of first-line treatment glucocorticoids on cell types of PV remain to be elucidated. We performing 5’ single-cell RNA seque...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 9964b96e-2c31-5c3d-8c8b-496f24911efb
DOI: 10.1101/2023.04.13.536499

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Single-Cell Transcriptomes and Immune Repertoires Reveal the Cell State and Molecular Changes in Pemphigus VulgarisDOI 10.1101/2023.04.13.536499Read

Single-Cell Transcriptome Analysis Reveals Interaction between CCL19+ Inflammatory Keratinocytes and CCR7+ Dendritic Cells and B Cells in PemphigusSemantic proximity Read

Single cell transcriptome profiling reveals pathogenesis of bullous pemphigoidSemantic proximity Read

Single-cell sequencing reveals distinct immune cell features in cutaneous lesions of pemphigus vulgaris and bullous pemphigoidSemantic proximity Read

Single cell transcriptome profiling reveals pathogenesis of Bullous PemphigoidSemantic proximity Read

Desmoglein-Specific B-Cell−Targeted Single-Cell Analysis Revealing Unique Gene Regulation in Patients with PemphigusSemantic proximity Read

The Pathogenic Role of CD4+ Tissue-Resident Memory T Cells Bearing T Follicular Helper-Like Phenotype in Pemphigus Lesions.Semantic proximity Read

Analysis of Gene Expression and TCR/B Cell Receptor Profiling of Immune Cells in Primary Sjögren’s Syndrome by Single-Cell SequencingSemantic proximity Read

Deep immune profiling pinpoints cellular and molecular drivers of lupus immunopathologySemantic proximity Read

Single-cell Landscape of Immune Cells in Blood and Skin in PsoriasisSemantic proximity Read

Cellular indexing of transcriptomes and epitopes (CITE-Seq) in hidradenitis suppurativa identifies dysregulated cell types in peripheral blood and facilitates diagnosis via machine learningSemantic proximity Read

Cytokine profiling reveals HLA-linked Th2 and Th17 driven immune activation in pemphigus vulgaris patients and genetically susceptible healthy controls.Semantic proximity Read

Single cell Transcriptome and T cell Repertoire Mapping of the Mechanistic Signatures and T cell Trajectories Contributing to Vascular and Dermal Manifestations of Behcet’s DiseaseSemantic proximity Read