Article
Ex vivo analysis of desmoglein 1-responsive T-helper (Th) 1 and Th2 cells in patients with pemphigus foliaceus and healthy individuals.
Experimental dermatology - 1 Aug 2005
Gebhard Kerstin L, Veldman Christian M, Wassmuth Ralf, Schultz Erwin, Schuler Gerold, Hertl Michael
Abstract excerpt
Pemphigus foliaceus (PF) is a severe autoimmune bullous disorder, characterized by autoantibodies (autoAb) against desmoglein 1 (Dsg1). As T cells may be critical in the pathology of PF, the aim of the present study was to identify and characterize autoaggressive T-helper cells reactive to Dsg1 i...
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