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Single cell transcriptome profiling reveals pathogenesis of bullous pemphigoid

8 Feb 2025

Abstract excerpt

Bullous pemphigoid (BP) triggers profound functional changes in both immune and non-immune cells in the skin and circulation, though the underlying mechanisms remain unclear. In this study, we conduct single-cell transcriptome analysis of lesional and non-lesional skin, as well as blood samples from BP patients. In lesional skin, non-immune cells upregulate pathways related to metabolism, wound healing, immune...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39922909
DOI: 10.1038/s42003-025-07629-4

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