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Article

Expression patterns of bone morphogenetic protein antagonists in colorectal cancer desmoplastic invasion fronts

19 Apr 2014

Abstract excerpt

Bone morphogenetic proteins (BMPs) are a group of growth factors with dual functions in cancer development and progression. Recently, certain tumor-promoting roles have been identified for selected antagonists/inhibitors (BMPIs) of this developmental pathway. A recent focus on the implication of BMP in colorectal cancer progression has emerged, mainly due to the presence of inactivating mutations in several...

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PMID: 24812030
DOI: 10.1016/j.molonc.2014.04.004

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