Article
Krüppel mediates the selective rebalancing of ion channel expression.
Neuron - 7 May 2014
Parrish Jay Z, Kim Charles C, Tang Lamont, Bergquist Sharon, Wang Tingting, Derisi Joseph L, Jan Lily Yeh, Jan Yuh Nung, Davis Graeme W
Abstract excerpt
Ion channel gene expression can vary substantially among neurons of a given type, even though neuron-type-specific firing properties remain stable and reproducible. The mechanisms that modulate ion channel gene expression and stabilize neural firing properties are unknown. In Drosophila, we demonstrate that loss of the Shal potassium channel induces the compensatory rebalancing of ion channel expression...
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