Article
Activity-independent homeostasis in rhythmically active neurons.
Neuron - 9 Jan 2003
MacLean Jason N, Zhang Ying, Johnson Bruce R, Harris-Warrick Ronald M
Abstract excerpt
The shal gene encodes the transient potassium current (I(A)) in neurons of the lobster stomatogastric ganglion. Overexpression of Shal by RNA injection into neurons produces a large increase in I(A), but surprisingly little change in the neuron's firing properties. Accompanying the increase in I(A) is a dramatic and linearly correlated increase in the hyperpolarization-activated inward current (I(h)). The...
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