Article
The Drosophila Shaker gene codes for a distinctive K+ current in a subset of neurons.
Neuron - 1 Jan 1990
Baker K, Salkoff L
Abstract excerpt
A transient K+ current coded by the Shaker gene was identified in muscle and expressed in Xenopus oocytes by injecting cRNA transcribed from a cloned cDNA. The Shaker current has not previously been identified in neurons. Mutational analysis now reveals that in neurons, Shaker is required for expression of a very rapidly inactivating K+ current with a depolarized steady-state inactivation curve. Together, these...
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