The Drosophila Shaker gene codes for a distinctive K+ current in a subset of neurons.

doi:10.1016/0896-6273(90)90449-p

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Article

The Drosophila Shaker gene codes for a distinctive K+ current in a subset of neurons.

Neuron - 1 Jan 1990

Baker K, Salkoff L

Abstract excerpt

A transient K+ current coded by the Shaker gene was identified in muscle and expressed in Xenopus oocytes by injecting cRNA transcribed from a cloned cDNA. The Shaker current has not previously been identified in neurons. Mutational analysis now reveals that in neurons, Shaker is required for exp...

Topics

Action Potentials
Animals
Blotting, Southern
Chromosome Deletion
Cloning, Molecular
Drosophila
Genes
Genotype
Neurons
Potassium Channels

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