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Article

Computational investigation of drug-resistant mutant of M2 proton channel (S31N) against rimantadine.

Cell biochemistry and biophysics - 1 Nov 2014

Karthick V, Ramanathan K

Abstract excerpt

M2 proton channel is the target for treating the patients who ere suffering from influenza A infection, which facilitates the spread of virions. Amantadine and rimantadine are adamantadine-based drugs, which target M2 proton channel and inhibit the viral replication. Preferably, rimantadine drug is used more than amantadine because of its fewer side effects. However, S31N mutation in the M2 proton channel was...

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Identifiers

PMID: 24807842
DOI: 10.1007/s12013-014-0005-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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