Article
TNF -308G > a promoter polymorphism (rs1800629) and outcome from critical illness.
The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases - 1 Jan 2000
Paskulin Diego D'Ávila, Fallavena Paulo Rv, Paludo Francis Jo, Borges Thiago J, Picanço Juliane B, Dias Fernando S, Alho Clarice Sampaio
Abstract excerpt
BACKGROUND: The susceptibility to adverse outcome from critical illness (occurrence of sepsis, septic shock, organ dysfunction/failure, and mortality) varies dramatically due to different degrees of inflammatory response. An over expression of tumor necrosis factor alpha (TNF-α) can lead to the p...
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