Article
Intronic and promoter polymorphisms of hMLH1/hMSH2 and colorectal cancer risk in Heilongjiang Province of China.
Journal of cancer research and clinical oncology - 1 Aug 2015
Li Guangxiao, Hu Fulan, Yuan Fengshun, Fan Jialong, Yu Zhifu, Wu Zhiwei, Zhao Xiaojuan, Li Ye, Li Shuying, Rong Jiesheng, Cui Binbin, Dong Xinshu, Yuan Huiping, Zhao Yashuang
Abstract excerpt
PURPOSE: Given that mismatch repair (MMR) system plays an important role in recognizing and removing insertion/deletion mutations which occur during DNA replication, common variants associated with impaired MMR system may thus increase risk of colorectal cancer (CRC). Therefore, we aimed to demon...
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