Article
IVS10+12A>G polymorphism in hMSH2 gene associated with prognosis for patients with colorectal cancer.
Annals of oncology : official journal of the European Society for Medical Oncology - 1 Mar 2010
Kim J G, Chae Y S, Sohn S K, Moon J H, Kang B W, Park J Y, Jeon S W, Lee M-H, Lim K-H, Choi G S, Jun S-H
Abstract excerpt
BACKGROUND: The polymorphisms in DNA repair genes may contribute to a variation in the DNA repair capacity, thereby affecting the risk of carcinogenesis and prognosis of colorectal cancer. Accordingly, the present study analyzed 14 polymorphisms in DNA repair genes and their impact on the prognosis for patients with colorectal cancer. MATERIALS AND METHODS: Three hundred and ninety-seven consecutive patients with...
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