Article
Genetic variation in interleukin 28B with respect to vertical transmission of hepatitis C virus and spontaneous clearance in HCV-infected children.
Hepatology (Baltimore, Md.) - 1 Jun 2011
Ruiz-Extremera Angeles, Muñoz-Gámez José Antonio, Salmerón-Ruiz María Angustias, de Rueda Paloma Muñoz, Quiles-Pérez Rosa, Gila-Medina Ana, Casado Jorge, Belén Martín Ana, Sanjuan-Nuñez Laura, Carazo Angel, Pavón Esther José, Ocete-Hita Esther, León Josefa, Salmerón Javier
Abstract excerpt
UNLABELLED: The vertical transmission of hepatitis C virus (HCV-VT) is a major route of HCV infection in children, but the risk factors remain incompletely understood. This study analyzed the role of interleukin 28B (IL28B) in HCV-VT and in the spontaneous clearance of HCV among infected infants. Between 1991 and 2009, 145 mothers were recruited for this study: 100 were HCV-RNA+ve / human immunodeficiency virus...
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