Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mouse genome-wide association and systems genetics identify Asxl2 as a regulator of bone mineral density and osteoclastogenesis.

PLoS genetics - 1 Apr 2011

Farber Charles R, Bennett Brian J, Orozco Luz, Zou Wei, Lira Ana, Kostem Emrah, Kang Hyun Min, Furlotte Nicholas, Berberyan Ani, Ghazalpour Anatole, Suwanwela Jaijam, Drake Thomas A, Eskin Eleazar, Wang Q Tian, Teitelbaum Steven L, Lusis Aldons J

Abstract excerpt

Significant advances have been made in the discovery of genes affecting bone mineral density (BMD); however, our understanding of its genetic basis remains incomplete. In the current study, genome-wide association (GWA) and co-expression network analysis were used in the recently described Hybrid...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bone Density
Share to Chromosomes, Mammalian

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Developmental

Share to Gene Regulatory Networks

Share to Molecular Sequence Annotation

Share to Osteoclasts

Share to Osteogenesis

Share to Repressor Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 21490954
DOI: 10.1371/journal.pgen.1002038
PMCID: PMC3072371

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21490954-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mouse genome-wide association and systems genetics identify Asxl2 as a regulator of bone mineral density and osteoclastogenesis.PMID 21490954Read ↗

Mouse genome-wide association and systems genetics identifies Lhfp as a regulator of bone massSemantic proximity Read ↗

Mouse Genome-Wide Association and Systems Genetics Identifies <i>Lhfp</i> as a Regulator of Bone MassSemantic proximity Read ↗

Bicc1 is a genetic determinant of osteoblastogenesis and bone mineral density.Semantic proximity Read ↗

An Atlas of Human and Murine Genetic Influences on OsteoporosisSemantic proximity Read ↗

Mouse mutant phenotyping at scale reveals novel genes controlling bone mineral density.Semantic proximity Read ↗

Systems genetics analyses in Diversity Outbred mice inform human bone mineral density GWAS and identify <i>Qsox1</i> as a novel determinant of bone strengthSemantic proximity Read ↗

A trans-eQTL network regulates osteoclast multinucleation and bone massSemantic proximity Read ↗

Integrating GWAS and Co-expression Network Data Identifies Bone Mineral Density Genes SPTBN1 and MARK3 and an Osteoblast Functional Module.Semantic proximity Read ↗

An integrative genetics approach to identify candidate genes regulating BMD: combining linkage, gene expression, and association.Semantic proximity Read ↗

Genome-wide association study in Collaborative Cross mice reveals a role for <i>Rhbdf2</i> in skeletal homeostasisSemantic proximity Read ↗

Identification of a Core Module for Bone Mineral Density through the Integration of a Co-expression Network and GWAS DataSemantic proximity Read ↗

Osteocyte Transcriptome Mapping Identifies a Molecular Landscape Controlling Skeletal Homeostasis and Susceptibility to Skeletal DiseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.