Article
Liver X receptor gene polymorphisms in tuberculosis: effect on susceptibility.
PloS one - 1 Jan 2014
Han Min, Liang Li, Liu Li-Rong, Yue Jun, Zhao Yan-Lin, Xiao He-Ping
Abstract excerpt
OBJECTIVES: The Liver X receptors (LXRs), Liver X receptor A (LXRA) and Liver X receptor B (LXRB), regulate lipid metabolism and antimicrobial response. LXRs have a crucial role in the control of Mycobacterium tuberculosis (M.tb). Lacking LXRs mice is more susceptibility to infection M.tb, develo...
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