Article
Polymorphisms in Toll-Like Receptor 10 and Tuberculosis Susceptibility: Evidence from Three Independent Series.
Frontiers in immunology - 1 Jan 2018
Wang Yu, Zhang Miao-Miao, Huang Wei-Wei, Wu Shou-Quan, Wang Ming-Gui, Tang Xiao-Yan, Sandford Andrew J, He Jian-Qing
Abstract excerpt
Background: The toll-like receptor 2 (TLR2)-mediated immune response is critical for host defense against Mycobacterium tuberculosis. There is evidence that TLR10, a TLR2 signaling modulator, may be involved in progression of tuberculosis (TB). Methods: Using a self-validating case-control design, we tested for an association between seven TLR10 polymorphisms and susceptibility to TB in three independent series...
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