Article
Vitamin D receptor gene associations with pulmonary tuberculosis in a Tibetan Chinese population.
BMC infectious diseases - 5 Sept 2016
Hu Qunying, Chen Zhengshuai, Liang Guinian, Mo Fangping, Zhang Hengxun, Xu Shilin, Wang Yuhe, Kang Longli, Jin Tianbo
Abstract excerpt
BACKGROUND: The vitamin D receptor (VDR) mediates the immunological function of vitamin D3, which activates macrophages, and vitamin D deficiency has been linked to tuberculosis risk. Single nucleotide polymorphisms (SNPs) in VDR may influence the function of vitamin D and susceptibility to tuberculosis. METHODS: This study included 217 patients with pulmonary tuberculosis (PTB) and 383 healthy subjects in a...
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