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Article

Discovery of susceptibility loci associated with tuberculosis in Han Chinese.

Human molecular genetics - 1 Dec 2017

Qi Hui, Zhang Yong-Biao, Sun Lin, Chen Cheng, Xu Biao, Xu Fang, Liu Jia-Wen, Liu Jin-Cheng, Chen Chen, Jiao Wei-Wei, Shen Chen, Xiao Jing, Li Jie-Qiong, Guo Ya-Jie, Wang Yong-Hong, Li Qin-Jing, Yin Qing-Qin, Li Ying-Jia, Wang Ting, Wang Xing-Yun, Gu Ming-Liang, Yu Jun, Shen A-Dong

Abstract excerpt

Genome-wide association studies (GWASs) have revealed the worldwide heterogeneity of genetic factors in tuberculosis (TB) susceptibility. Despite having the third highest global TB burden, no TB-related GWAS has been performed in China. Here, we performed the first three-stage GWAS on TB in the Han Chinese population. In the stage 1 (discovery stage), after quality control, 691 388 SNPs present in 972 TB patients...

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Identifiers

PMID: 29036319
DOI: 10.1093/hmg/ddx365

Genes

MFN2
RGS12

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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