Article
SFRP1 variations influence susceptibility and immune response to Mycobacterium tuberculosis in a Chinese Han population.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Jan 2016
Zhao Zhenzhen, Peng Wu, Hu Xuejiao, Zhang Jingya, Shang Mengqiao, Zhou Juan, Zhou Yi, Song Xingbo, Lu Xiaojun, Ying Binwu, Chen Xuerong
Abstract excerpt
OBJECTIVES: SFRP1 acts as a well-established inhibitory regulator of the Wnt signaling pathway, whose polymorphisms have been demonstrated to be associated with the risk of inflammation, infection as well as cancer. We verified the hypothesis that single nucleotide polymorphisms (SNPs) within SFRP1 gene are associated with susceptibility and clinical characteristics of tuberculosis disease in a Chinese Han...
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