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Article

A programmable method for massively parallel targeted sequencing.

Nucleic acids research - 1 Jun 2014

Hopmans Erik S, Natsoulis Georges, Bell John M, Grimes Susan M, Sieh Weiva, Ji Hanlee P

Abstract excerpt

We have developed a targeted resequencing approach referred to as Oligonucleotide-Selective Sequencing. In this study, we report a series of significant improvements and novel applications of this method whereby the surface of a sequencing flow cell is modified in situ to capture specific genomic regions of interest from a sample and then sequenced. These improvements include a fully automated targeted sequencing...

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Identifiers

PMID: 24782526
DOI: 10.1093/nar/gku282
PMCID: PMC4041455

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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