Article
Inter-individual variation in DNA repair capacity: a need for multi-pathway functional assays to promote translational DNA repair research.
DNA repair - 1 Jul 2014
Nagel Zachary D, Chaim Isaac A, Samson Leona D
Abstract excerpt
Why does a constant barrage of DNA damage lead to disease in some individuals, while others remain healthy? This article surveys current work addressing the implications of inter-individual variation in DNA repair capacity for human health, and discusses the status of DNA repair assays as potential clinical tools for personalized prevention or treatment of disease. In particular, we highlight research showing...
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