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Article

Genetic dissection of intermediate phenotypes as a way to discover novel cancer susceptibility alleles.

Current opinion in genetics & development - 1 Jun 2010

Carvajal-Carmona Luis G

Abstract excerpt

The availability of affordable genome-wide association (GWA) studies has led to the discovery of a large number of cancer risk alleles. The prospects of identifying additional alleles using the same disease-based approach are limited unless very large samples sizes are used in future investigations. An alternative and powerful way to identify additional cancer genes is to study intermediate phenotypes, such as...

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PMID: 20456939
DOI: 10.1016/j.gde.2010.03.013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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