Article
Phenotyping for DNA repair capacity.
Mutation research - 1 Oct 2010
Decordier Ilse, Loock Kim Vande, Kirsch-Volders Micheline
Abstract excerpt
The ability to repair DNA damage is strongly associated with the risk of cancer and other human diseases as it is essential for maintenance of genome stability. Moreover, DNA repair capacity is an important factor contributing to the inter-individual variability in mutagen exposure, cancer development and treatment through an individualized adjusted therapy. In addition to genotypes, functional phenotypic assays...
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