DNA Repair: From Genome Maintenance to Biomarker and Therapeutic Target

doi:10.1158/1078-0432.ccr-11-0761

Article

DNA Repair: From Genome Maintenance to Biomarker and Therapeutic Target

10 Sept 2011

Abstract excerpt

A critical link exists between an individual's ability to repair cellular DNA damage and cancer development, progression, and response to therapy. Knowledge gained about the proteins involved and types of damage repaired by the individual DNA repair pathways has led to the development of a variety of assays aimed at determining an individual's DNA repair capacity. These assays and their use in the analysis of...

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.