Article
Variation in DNA repair is a factor in cancer susceptibility: a paradigm for the promises and perils of individual and population risk estimation?
Mutation research - 25 May 1998
Mohrenweiser H W, Jones I M
Abstract excerpt
The repair of DNA damage protects the genome of the cell from the insults of cancer causing agents. This was originally demonstrated in individuals with the rare genetic disease, xeroderma pigmentosum, the prototype of cancer genes, and subsequently in the relationship of mismatch repair to colon...
Topics
- Animals
- DNA Repair
- Disease Susceptibility
- Genetic Variation
- Humans
- Neoplasms
- Oncogenes
- Risk Assessment
