Article

Molecular characterization of Cdh12-SCON conditional knockout mice reveals unexpected splicing changes

2025-12-11

Abstract excerpt

Functional validation of candidate genes in congenital anomalies of the kidneys and urinary tract (CAKUT) and other disorders is essential for translating genetic discoveries into clinical applications. Conditional knockout mouse models are indispensable for studying gene function in complex organ systems. The Short Conditional intrON (SCON) system accelerates the generation of such models by inserting the artific...

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Literature Corpus work: 68265f74-00c8-51a9-8b6a-ddd1cf313e8a
DOI: 10.64898/2025.12.09.693148

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