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Article

Generation of Conditional Knockout Alleles for PRUNE-1.

Cells - 6 Feb 2023

Wu Xiaoli, Simard Louise R, Ding Hao

Abstract excerpt

PRUNE1 is a member of the aspartic acid-histidine-histidine (DHH) protein superfamily, which could display an exopolyphosphatase activity and interact with multiple cellular proteins involved in the cytoskeletal rearrangement. It is widely expressed during embryonic development and is essential for embryogenesis. PRUNE1 could also be critical for postnatal development of the nervous system as it was found to be...

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PMID: 36831191
DOI: 10.3390/cells12040524
PMCID: PMC9954577

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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