Article
Exonic single nucleotide polymorphisms within TLR3 associated with infant responses to serogroup C meningococcal conjugate vaccine.
Vaccine - 5 Jun 2014
O'Connor Daniel, Moore Catrin E, Snape Matthew D, John Tessa, Hill Adrian V S, Pollard Andrew J
Abstract excerpt
The introduction of the serogroup C meningococcal (MenC) conjugate vaccination has successfully controlled the burden of disease associated with this serogroup in many countries. However, considerable inter-individual variation is observed in immune responses to MenC vaccine, and little is understood of the determinants of this variability. Previously, we reported an association between single nucleotide...
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